Partners
City of Hope
Founded in 1913, City of Hope is a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, and is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. PeproMene had licensed the development rights of anti-BAFFR antibodies, BAFFR CAR T cell therapy and BAFF-R BiTE from City of Hope. PeproMene also collaborates with City of Hope to manufacture BAFFR CAR T cells using in its GMP facilities, the Cellular Therapy Production Center and the Center for Biomedicine & Genetics. Currently, BAFFR CAR-T Cells (PMB-CT01) phase 1 clinical trials are being conducted at City of Hope for treating relapsed and refractory B-cell acute lymphoblastic leukemia and mantle cell lymphoma.